Search results for "Carbohydrate deficient transferrin"

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Carbohydrate-deficient transferrin (CDT) and HDL cholesterol (HDL) are highly correlated in male alcohol dependent patients.

2000

Background: Serum levels of total HDL cholesterol (HDL) are reportedly influenced by recent alcohol intake. We examined the correlation between HDL cholesterol and widely used markers of excessive alcohol intake, such as carbohydrate-deficient transferrin (CDT), γ-glutamyl-transferase (GGT), or mean corpuscular volume of erythrocytes (MCV), of which CDT is thought to be the most specific. Methods: Several serological markers [i.e., CDT, GGT, aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), MCV, and HDL] were determined in 100 actively drinking male patients with alcohol dependence (DSM-IV) and in 27 non-alcohol-dependent controls, according to routine procedures. Spearman…

AdultErythrocyte IndicesMalemedicine.medical_specialtyAdolescentCarbohydrate deficient transferrinMedicine (miscellaneous)AlcoholToxicologyStatistics Nonparametricchemistry.chemical_compoundInternal medicinemedicineHumansMean corpuscular volumeAgedchemistry.chemical_classificationEthanolmedicine.diagnostic_testbusiness.industryCholesterolAlcohol dependenceCholesterol HDLTransferringamma-GlutamyltransferaseMiddle AgedPsychiatry and Mental healthAlcoholismEndocrinologychemistryTransferrinToxicitylipids (amino acids peptides and proteins)businessBiomarkersAlcoholism, clinical and experimental research
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Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol-dependent patients.

2001

- Vitamin B12 serum levels and markers for alcohol consumption were determined in 80 male alcohol-dependent patients. Spearman correlation coefficients (r(S)) were calculated. Significant positive correlations between vitamin B12 and hepatic enzyme values were found (gamma-glutamyltransferase: r(S) = 0.58; alanine aminotransferase: r(S) = 0.43; aspartate aminotransferase: r(S) = 0.47; glutamate dehydrogenase: r(S) = 0.43; all P:0.001). Therefore, for a proper interpretation of vitamin B12 levels, it may be clinically relevant to take markers of hepatocellular damage into account.

AdultErythrocyte IndicesMalemedicine.medical_specialtyCarbohydrate deficient transferrinAspartate transaminaseStatistics NonparametricGlutamate DehydrogenaseInternal medicineBlood plasmamedicineHumansCyanocobalaminVitamin B12Aspartate AminotransferasesLiver Diseases AlcoholicRetrospective StudiesbiologyGlutamate dehydrogenaseTransferrinnutritional and metabolic diseasesAlanine TransaminaseGeneral Medicinegamma-GlutamyltransferaseMiddle AgedAlcoholismVitamin B 12EndocrinologyAlanine transaminaseLiverToxicitybiology.proteinBiomarkersAlcohol and alcoholism (Oxford, Oxfordshire)
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